reference compound cddo me (Selleck Chemicals)
Selleck Chemicals is a verified supplier 
Selleck Chemicals manufactures this product 
96
Structured Review
Selleck Chemicals
reference compound cddo me
Reference Compound Cddo Me, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1290 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/reference+compound/Compound/pm41786067-90-21-24
Average 96 stars, based on 1290 article reviews
Reference Compound Cddo Me, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1290 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/reference+compound/Compound/pm41786067-90-21-24
Average 96 stars, based on 1290 article reviews
reference compound cddo me - by Bioz Stars,
2026-10
96/100 stars
Images
Related Articles
Concentration Assay:Article Title: Compounds and methods of use Article Snippet: Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Reference compound 1: EPZ015666 (GSK3235025) (SelleckChem, cat #57748-5 mgs, 10 mM in DMSO) Reference compound 2: (S)-2-(cyclobutylamino)-N-(3-(8,9-dihydro-[1,3]dioxolo[4,5-f]isoquinolin-7(6H)-yl)-2-hydroxypropyl)isonicotinamide (Tango, 10 mM in DMSO) Assay Conditions: Study compound and reference compound concentration: 3-fold serial dilution from 125 μM Each assay plate contains the above two reference compounds DMSO concentration in each well: 1.25% DMSO Compound IC50 was determined in 3 assay conditions: 1. .. Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Article Title: Compounds and methods of use Article Snippet: .. Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Article Title: Compounds and methods of use Article Snippet: .. Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Article Title: Compounds and methods of use Article Snippet: .. Study Compounds and Serial Dilution:Article Title: Compounds and methods of use Article Snippet: Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Reference compound 1: EPZ015666 (GSK3235025) (SelleckChem, cat #57748-5 mgs, 10 mM in DMSO) Reference compound 2: (S)-2-(cyclobutylamino)-N-(3-(8,9-dihydro-[1,3]dioxolo[4,5-f]isoquinolin-7(6H)-yl)-2-hydroxypropyl)isonicotinamide (Tango, 10 mM in DMSO) Assay Conditions: Study compound and reference compound concentration: 3-fold serial dilution from 125 μM Each assay plate contains the above two reference compounds DMSO concentration in each well: 1.25% DMSO Compound IC50 was determined in 3 assay conditions: 1. .. Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Article Title: Compounds and methods of use Article Snippet: .. Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Article Title: Compounds and methods of use Article Snippet: .. Study Compounds and Reference Compounds: Study compounds are dissolved in DMSO starting with a stock concentration of 10 mM Article Title: Compounds and methods of use Article Snippet: .. Study Compounds and other:Article Title: Compounds and methods of use Article Snippet: No cofactor+25 nM Me0+100 nM PRMT5 Materials: Reagents Vendor Bicine pH 8.0, 0.5M Alfa Aesar, Cat# A14957 Sodium Chloride, 5M Sigma-Aldrich, Cat# S5150 Tween-20, 10% Sigma-Aldrich, Cat# 11332465001 DL-Dithiothreitol or DTT, 0.5M in Sigma-Aldrich, Cat# 43816 water PRMT5:MEP50, 51 μM; Storage Viva custom protein Buffer 50 mM Tris, 250 mM NaCl, 1 mM TCEP, pH 8.0 Me0-PEP21, Unmethylated Peptide, Anaspec custom order 1.9 mM in water Me2-PEP21-sDMA, Dimethylated Anaspec custom order Peptide, 1.9 mM in water Dimethyl Sulfoxide Sigma-Aldrich, Cat# D8418-1L S-adenosyl methionine (SAM), CAYMAN CHEMICAL, 32 mM Cat# 0461501-31 methylthioadenosine (MTA), EMD Millipore, Cat# 260585 25 mM Preparation of Cofactor Solutions SAM was dissolved in distilled deionized water to make a 32 mM solution, which was stored at −20° C. and discarded after one freeze-thaw cycle MTA—was dissolved in distilled deionized water to make 2.5 mM stock solution. Article Title: Compounds and methods of use Article Snippet: The mixture was concentrated under reduced pressure to give a crude product, which was purified by preparative HPLC (Instrument: Gilson GX-281 Liquid Handler, Gilson 322 Pump, Gilson 156 UV Detector; Column: Waters Xbridge 150×50 mm×10 μm; Mobile phase A: H2O with 0.05% NH3—H2O (v %); Mobile phase B: MeCN; Gradient: B from 12% to 42% in 9.5 min, hold 100% B for 2 min; Flow Rate: 25 mL/min; Column Temperature: 30° C.; Wavelength: 220 nm, 254 nm) to give 6-[(1-acetyl-4-piperidyl)amino]-N-[(2S)-2-hydroxy-3-[2-(oxazol-5-ylmethoxy)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]propyl]pyrimidine-4-carboxamide (13 mg, 27.3% yield) as a white dry powder. |